SCORE assessed the credibility of research claims through large-scale reproducibility, robustness, and replication tests of hundreds of published findings from the social and behavioral sciences, alongside human and machine assessments of replicability. The collection, to be published in Nature in 2026, provides a broad empirical look at how research claims fare under different forms of scrutiny and what scalable assessment methods may contribute to evaluating trustworthiness.
A large-scale, crowdsourced project to examine the replicability of published findings in health research. The project aims to assess the robustness of findings and promote best practices in research transparency, methodological rigor, and reproducibility in support of a more transparent and trustworthy foundation for health research.
These ongoing activities reflect current areas of work, including active research, pilots, and partnerships designed to generate evidence, test new approaches, and inform future innovation.
Developing a framework for evaluating LLM agents ability to perform components of the research process. Exploring the opportunities and limitations of LLM agents supporting rigorous and trustworthy research practices.
An open, modular survey assessing attitudes, behaviors, perceptions, and blockers for adopting open science practices. We administer the survey and provide reports for research supporting organizations to understand the state of practice in their community and opportunities for improving engagement with open science.
OSF is a rich resource of research behavior beyond the published article. Metascientists can employ the public API to conduct investigations of the research process.
These archived activities reflect a longer portfolio of metascience research examining credibility, transparency, and innovative methods across different fields and methods. While these projects are no longer active, they continue to inform COS’s current research, products, and solutions.
Replications of 193 papers and 53 findings from high-impact pre-clinical cancer biology papers. Published in eLife in 2021. Replication meta-analysis (Errington et al., 2021a). Challenges conducting replications (Errington et al., 2021b). Journal collection of papers. OSF collection of data, materials, and code.

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COS has earned top recognition from Charity Navigator and Candid (formerly GuideStar) for our financial transparency and accountability to our mission. COS and the OSF were also awarded SOC2 accreditation in 2023 after an independent assessment of our security and procedures by the American Institute of CPAs (AICPA).
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